Throughout the world, every biopharmaceutical company and university are working for developing an effective COVID-19 vaccine to combat SARs-COV-2(Severe Acute Respiratory Syndrome Coronavirus 2).

some biopharmaceutical companies and universities are going with human clinical trials at this time.

1.Cansino Biological INc/Beijing Institute of technology: Cansino Biological INc is a biopharmaceutical company in china that is worked on vaccine research and development, commercialization. In march 17,2020 recombinant novel coronavirus (Adenovirus type 5 vector)candidate has been approved for a human clinical trial. It is ongoing on clinical phase trial I.

2.Inovia pharmaceuticals: Inovia pharmaceuticals ia biotechnology company that is worked on DNA. This company developed a DNA vaccine that is an ongoing human clinical phase I trial. The of the vaccine is INO-4800. Pre-clinical animal models gave a good result according to data.

3.BEIJING INSTITUTE OF BIOLOGICAL PRODUCT: This company is worked on research and development, supplying vaccines to various companies. this company collaborated with some institutions and developed an inactivated vaccine. The inactivated vaccine developed by Wuhan Institute of Biological Products under the China National Pharmaceutical Group (Sinopharm)
and the Wuhan Institute of Virology under the Chinese Academy of Sciences started its clinical trial on April 12. According to developers, 26 April 2020 inactivated vaccine entered the second phase of a human clinical trial.

4.Sinovac pharmaceutical company: Sinovac is a biopharmaceutical company that is present in China. This company is basically worked on research , development of a vaccine, and also manufacturing vaccine of infectious disease. The Company started the development of a vaccine against COVID-19 at the last of January 2020. The NMPA gave approval for human trials on April 13, 2020.
 The phase I study commenced on April 16. The trial is ongoing.

5.Moderna: Moderna is an American based biotechnology company that is worked on drug development and drug delivery on the basis of mRNA.On Jan 11, 2020, when china released the sequence of the coronavirus Moderna developed an mRNA-1273 vaccine. this vaccine is on phase I clinical trial.

6.BioNTech company: Biopharmaceutical New Technologies (BioNTech) is a next-generation immunotherapy company discovering novel therapies for cancer and infectious diseases. The Company uses a wide collection of computational discovery and therapeutic drug programs for the rapid development of new biopharmaceuticals.BioNTech company has developed a vaccine that is known as a BNT-162. April 29, 2020, BioNTech and Pfizer Inc. have declared that the first group of BioNTech’s Phase 1/2 clinical trial has been dosed. Twelve study members were dosed with vaccine candidate BNT162 in Germany since dosing occurred on April 23, 2020.

7.Oxford University, Jenner's institute(oxford vaccine group): Oxford university developed ChAdOx1 nCoV-19 is made from a virus ChAdOx1, which is a weakened variant of a common cold virus that causes infections in chimpanzees, that has been genetically modified so that it is difficult for it to grow in humans. The oxford university has declared an agreement with the UK-based global biopharmaceutical company AstraZeneca for more development, large-scale manufacture, and a possible number of the COVID-19 vaccine candidate currently being trialed by the Oxford Vaccine Group.

 When will a COVID-19 vaccine Be Available? || Why It is take 12-18 Month.

 Sources:
http://www.cansinotech.com/
https://www.inovio.com/
http://www.sinovac.com/
https://www.modernatx.com/
https://biontech.de/
https://www.ovg.ox.ac.uk/